Eastern Panama Vacation Packages

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Top Eastern Panama Vacation Deals

Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel

3.5 out of 5
Amador
per person
Apr. 10 - Apr. 17
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
8/10 Very Good! (65 reviews)
Older hotel, sqeeky clean room, staff was awesome. Elevator broke and staff helped bring luggage downstairs. Our room was in the middle on the back side was able sleep well.

Reviewed on Feb. 17, 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
May 2 - May 7
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9/10 Wonderful! (810 reviews)
Beautiful historic hotel in the middle of Casco Viejo. Perfect location for exploring.

Reviewed on Feb. 20, 2025

Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Save 100% on your flight
per person
Apr. 15 - Apr. 22
found 15 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9.4/10 Exceptional! (91 reviews)
Absolutely beautiful and charming old inn. Gorgeous grounds. Excellent dinner on the restaurant. Very helpful staff.

Reviewed on Feb. 7, 2025

Summit Rainforest & Golf Resort

Summit Rainforest & Golf Resort

4 out of 5
per person
Apr. 10 - Apr. 17
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
8.4/10 Very Good! (1,000 reviews)
The room and bed were great The restaurant offered great breakfast buffet and the lunch and dinner menus had plenty of options. We enjoyed the one hour walking tour. We enjoyed the size of the pool; however, the water was very cloudy, thus questionable.

Reviewed on Feb. 15, 2025

NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Save 100% on your flight
per person
Apr. 15 - Apr. 22
found 15 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
10/10 Exceptional! (45 reviews)
My wife and I just returned from a five night stay at Nayara. The amazing reviews you read prior to your arrival will be met with complete accuracy. We really enjoyed the uniqueness of the treehouse where we enjoyed three of our five nights. We spent our final two nights in the overwater villa which was incredible as well. We’ve traveled to many destinations in the past, but have never been met with such kindness and the willingness of the Nayara staff to go out of their way to ensure your satisfaction. Every staff member we met exceeded our expectations. Carlos, Franco, Cheryl, Jesus, Ruby, Jenny and my buddy from Venezuela all made a lasting impact on us that we will always remember. We can’t wait to see you again!

Reviewed on Feb. 5, 2025

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Eastern Panama Hotel Deals

Ciel y Miel
Ciel y Miel
3 out of 5
Caillle Principale, Cacique, Provincia de Colón
The price is CA $326 per night from Feb. 23 to Feb. 24
CA $326
CA $359 total
includes taxes & fees
Feb 23 - Feb 24
10/10 Exceptional! (1 review)
"Love this place and would return back numerous times"

Reviewed on Feb. 12, 2025

Ciel y Miel
San Blas Paradise Private Cabins on Shipwreck Island - meals included
San Blas Paradise Private Cabins on Shipwreck Island - meals included
2 out of 5
Perro Island, Narganá, Guna Yala
The price is CA $319 per night from Feb. 26 to Feb. 27
CA $319
CA $351 total
includes taxes & fees
Feb 26 - Feb 27
San Blas Paradise Private Cabins on Shipwreck Island - meals included
Private Ocean-Front Cabin with private bathroom on San Blas Island
Private Ocean-Front Cabin with private bathroom on San Blas Island
2 out of 5
Diablo Island, Narganá, Guna Yala
The price is CA $296 per night from Feb. 23 to Feb. 24
CA $296
CA $326 total
includes taxes & fees
Feb 23 - Feb 24
Private Ocean-Front Cabin with private bathroom on San Blas Island
See all 177 properties in Eastern Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does an Eastern Panama vacation package cost?
The most affordable Eastern Panama vacation package is CA $925, so your dream getaway can become a reality — without breaking the bank. Bundle flights, hotels and car rentals to tailor make a package that matches your traveling style.
How do I get a cheap travel package to Eastern Panama?
Lock in flights that suit your schedule, add a hotel to your booking and watch the savings pile up with an Eastern Panama vacation package. It’s as simple as that! From flights and hotels to rental cars and activities, Expedia is where your cheap getaway begins. And with over 550 air carriers and 1,000,000 hotels around the world to choose from, you won’t be short of choice.
What are the top hotels in Eastern Panama?
For hotels in San Blas Islands with friendly service and cozy beds, look up Private Over The Water Cabin On San Blas Island and San Blas Private Over - The - Water Cabin. If you plan to explore Narganá as well, you can look forward to a great night’s sleep at Paradise Over The Water Cabins In San Blas or San Blas Private Over - The - Water Cabin.
How far in advance should I book my Eastern Panama vacation?
Smart travelers often reserve their seats as early as possible. You can generally look up international fares on Expedia up to 12 months before your intended flight. If you’re booking last minute, don’t despair. Low prices sometimes occur just weeks prior to departure.
What does an Expedia Eastern Panama travel package include?
Flights, rental cars and hotels, or any combination of the three — it’s your choice. Whether you’re visiting Eastern Panama with the kids or traveling by yourself, there’s a package to fit every style and budget. Once you’ve made your booking, why not add on a couple of tours or activities?
What should I know before booking an Eastern Panama travel package?
Booking all the parts of your getaway together is an excellent way to save. Combine your car rentals, flights and hotels into a neat little package. But it’s not just hotels. Expedia features all types of properties, including vacation rentals like mountain cabins and city apartments. Your choices are almost endless!
Can I choose my airline with an Eastern Panama Expedia vacation package?
Yes — that’s the beauty of an Expedia vacation package. You’re in charge! We have access to more than 550 airline partners across the globe, so you have loads of choice when planning your Eastern Panama getaway.
If I'm not able to travel, can I cancel my Eastern Panama vacation package?
You can. We realize life doesn’t always go to plan, so we’re happy to help if you have to make changes to your Eastern Panama vacation package. You may be able to cancel or change your itinerary for free if you’ve booked within 24 hours. Your hotel, airline or car rental company may charge you a fee if your booking was made more than 24 hours ago. Look up our Customer Service Portal for more information. Also, check your itinerary for the finer details on change fees.

Discover the most popular places to visit in Eastern Panama

Cayos Holandeses

Commune with nature and explore the great outdoors at Cayos Holandeses during your travels in San Blas Islands. Stroll along the seaside or experience the area's festivals.

Cayos Holandeses
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.