Eastern Panama Vacation Packages

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Your Eastern Panama Vacation

Leave all the planning to us with an Eastern Panama vacation package. With everything organized before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama vacation into reality.

Top Eastern Panama Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Jul. 19 - Jul. 26
found 1 day ago
Roundtrip non-stop flight included
Montreal (YUL) to Panama City (PTY)
9.8/10 Exceptional! (56 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr. 18, 2025

Residencia Natural

Residencia Natural

3 out of 5
per person
Jul. 20 - Jul. 27
found 1 day ago
Roundtrip non-stop flight included
Montreal (YUL) to Panama City (PTY)
10/10 Exceptional! (6 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Jul. 19 - Jul. 26
found 1 day ago
Roundtrip non-stop flight included
Montreal (YUL) to Panama City (PTY)
9/10 Wonderful! (863 reviews)
The hotel was lovely and staff very friendly. Great location.

Reviewed on Apr. 13, 2025

Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
Jul. 20 - Jul. 27
found 1 day ago
Roundtrip non-stop flight included
Montreal (YUL) to Panama City (PTY)
8.6/10 Excellent! (139 reviews)
Good place for relax and enjoy good vacations with the family

Reviewed on Apr. 6, 2025

La Coralina Island House

La Coralina Island House

3.5 out of 5
per person
Jul. 20 - Jul. 27
found 1 day ago
Roundtrip non-stop flight included
Montreal (YUL) to Panama City (PTY)
9.4/10 Exceptional! (73 reviews)
I went with my son for his birthday and it was amazing, very pricey but celebrated his 16th birthday and we had a blast! The hotel staff made it very special for us and they were excellent. We enjoyed all 3 nights there.

Reviewed on Apr. 23, 2025

Ready to book your vacation to Eastern Panama?

 

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Eastern Panama Hotel Deals

Ordovician Beach Resort
Ordovician Beach Resort
4.5 out of 5
Isla Grande, Isla Grande, Colon
The price is CA $747 per night from Apr. 30 to May 1
CA $747
CA $822 total
includes taxes & fees
Apr 30 - May 1
Ordovician Beach Resort
Ciel y Miel
Ciel y Miel
3 out of 5
Caillle Principale, Cacique, Provincia de Colón
The price is CA $318 per night from Apr. 30 to May 1
CA $318
CA $350 total
includes taxes & fees
Apr 30 - May 1
10/10 Exceptional! (4 reviews)
"Is an execelent place to relax, enjoy nice food and view. It has access to a beautiful beach which is not overcrowded and the staff is on top of everything. Me and my family are definetly coming back!!!"

Reviewed on Mar. 3, 2025

Ciel y Miel
Private Over the Water Cabin on San Blas Island
Private Over the Water Cabin on San Blas Island
2 out of 5
9.542876, -78.899058, Narganá, San Blas
The price is CA $289 per night from Apr. 30 to May 1
CA $289
CA $318 total
includes taxes & fees
Apr 30 - May 1
6.4/10 (5 reviews)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were ..."

Reviewed on Feb. 16, 2022

Private Over the Water Cabin on San Blas Island
See all 159 properties in Eastern Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does an Eastern Panama vacation package cost?
The most affordable Eastern Panama vacation package is CA $1,457, so your dream getaway can become a reality — without breaking the bank. Bundle flights, hotels and car rentals to tailor make a package that matches your traveling style.
How do I get a cheap travel package to Eastern Panama?
Lock in flights that suit your schedule, add a hotel to your booking and watch the savings pile up with an Eastern Panama vacation package. It’s as simple as that! From flights and hotels to rental cars and activities, Expedia is where your cheap getaway begins. And with over 550 air carriers and 1,000,000 hotels around the world to choose from, you won’t be short of choice.
What are the top hotels in Eastern Panama?
For hotels in San Blas Islands with friendly service and cozy beds, look up Private Over The Water Cabin On San Blas Island and San Blas Private Over - The - Water Cabin. If you plan to explore Narganá as well, you can look forward to a great night’s sleep at Paradise Over The Water Cabins In San Blas or San Blas Private Over - The - Water Cabin.
How far in advance should I book my Eastern Panama vacation?
Smart travelers often reserve their seats as early as possible. You can generally look up international fares on Expedia up to 12 months before your intended flight. If you’re booking last minute, don’t despair. Low prices sometimes occur just weeks prior to departure.
What does an Expedia Eastern Panama travel package include?
Flights, rental cars and hotels, or any combination of the three — it’s your choice. Whether you’re visiting Eastern Panama with the kids or traveling by yourself, there’s a package to fit every style and budget. Once you’ve made your booking, why not add on a couple of tours or activities?
What should I know before booking an Eastern Panama travel package?
Booking all the parts of your getaway together is an excellent way to save. Combine your car rentals, flights and hotels into a neat little package. But it’s not just hotels. Expedia features all types of properties, including vacation rentals like mountain cabins and city apartments. Your choices are almost endless!
Can I choose my airline with an Eastern Panama Expedia vacation package?
Yes — that’s the beauty of an Expedia vacation package. You’re in charge! We have access to more than 550 airline partners across the globe, so you have loads of choice when planning your Eastern Panama getaway.
If I'm not able to travel, can I cancel my Eastern Panama vacation package?
You can. We realize life doesn’t always go to plan, so we’re happy to help if you have to make changes to your Eastern Panama vacation package. You may be able to cancel or change your itinerary for free if you’ve booked within 24 hours. Your hotel, airline or car rental company may charge you a fee if your booking was made more than 24 hours ago. Look up our Customer Service Portal for more information. Also, check your itinerary for the finer details on change fees.

Discover the most popular places to visit in Eastern Panama

Cayos Holandeses

Commune with nature and explore the great outdoors at Cayos Holandeses during your travels in San Blas Islands. Stroll along the seaside or experience the area's festivals.

Cayos Holandeses
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.